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Fas Activated Serine/Threonine Kinase (FASTK) Antibody
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Catalogue No: abx005347
Price:
US$217.50
(Size: 20 µl)
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FASTK Antibody is a Rabbit Polyclonal antibody against FASTK. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
Research Articles on Fas Activated Serine/Threonine Kinase (FASTK)
| Target | Fas Activated Serine/Threonine Kinase (FASTK) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 360-549 of human FASTK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14296 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K867, F8VTW9, Q59EM8, Q8IVA0 |
| UniProt Entry Name | FASTK_HUMAN |
| Gene Symbol | FASTK |
| GeneID | 10922 |
| NCBI Accession | NP_006703.1 |
| KEGG | hsa:10922 |
| String | 9606.ENSP00000297532 |
| Molecular Weight | Calculated MW: 61 kDa Observed MW: 61 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |