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Fibrillarin (FBL) Antibody
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Catalogue No: abx031701
Price:
US$326.25
(Size: 80 µl)
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FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. This protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
Research Articles on Fibrillarin (FBL)
| Target | Fibrillarin (FBL) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 105-135 amino acids from the Central region of human FBL. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P22087 (UniProt, ExPASy) |
| UniProt Secondary AC | B5BUE8, O75259, Q6IAT5, Q9UPI6 |
| UniProt Entry Name | FBRL_HUMAN |
| KEGG | hsa:2091 |
| String | 9606.ENSP00000221801 |
| Molecular Weight | Calculated MW: 33.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat FBL. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |