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Fibulin 5 (FBLN5) Antibody
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Catalogue No: abx010772
Price:
US$427.75
(Size: 100 µl)
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FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.
Research Articles on Fibulin 5 (FBLN5)
| Target | Fibulin 5 (FBLN5) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UBX5 (UniProt, ExPASy) |
| UniProt Secondary AC | O75966, Q6IAL4, Q6UWA3 |
| UniProt Entry Name | FBLN5_HUMAN |
| Gene Symbol | FBLN5 |
| GeneID | 10516 |
| OMIM | 219100 |
| HGNC | 3602 |
| Ensembl | ENSG00000140092 |
| String | 9606.ENSP00000345008 |
| Molecular Weight | 50 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |