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F-Box Protein 32 (FBXO32) Antibody
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Catalogue No: abx005224
Price:
US$203.00
(Size: 20 µl)
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FBXO32 Antibody is a Rabbit Polyclonal antibody against FBXO32. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on F-Box Protein 32 (FBXO32)
| Target | F-Box Protein 32 (FBXO32) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 206-355 of human Fbx32/FBXO32. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q969P5 (UniProt, ExPASy) |
| UniProt Secondary AC | A4KYM0 |
| UniProt Entry Name | FBX32_HUMAN |
| Gene Symbol | FBXO32 |
| GeneID | 114907 |
| NCBI Accession | NP_478136.1 |
| KEGG | hsa:114907 |
| String | 9606.ENSP00000428205 |
| Molecular Weight | Calculated MW: 42 kDa Observed MW: 40 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |