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F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody
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Catalogue No: abx026152
Price:
US$290.00
(Size: 80 µl)
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Research Articles on F-Box And WD Repeat Domain Containing 11 (FBXW11)
| Target | F-Box And WD Repeat Domain Containing 11 (FBXW11) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 168-196 amino acids from the Central region of human FBXW11. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UKB1 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RC98, Q9P2S8, Q9P2S9, Q9Y4C6 |
| UniProt Entry Name | FBW1B_HUMAN |
| Gene Symbol | FBXW11 |
| String | 9606.ENSP00000265094 |
| Molecular Weight | Calculated MW: 62.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse FBXW11. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |