Fibrinogen Alpha (FGA) Antibody

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq].

Target	Fibrinogen Alpha (FGA)
Clonality	Monoclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 420-448 amino acids from the N-terminal region of human FGA.
Isotype	IgM
Form	Liquid
Purification	Purified Mouse Monoclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P02671 (UniProt, ExPASy)
UniProt Secondary AC	A8K3E4, D3DP14, D3DP15, Q4QQH7, Q9BX62, Q9UCH2
UniProt Entry Name	FIBA_HUMAN
KEGG	hsa:2243
String	9606.ENSP00000306361
Molecular Weight	Calculated MW: 95 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fibrinogen Alpha (FGA)

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