+44 (0) 1223 755950
+1 832 327 7413
Fibrinogen Beta (FGB) Antibody
REQUEST MORE INFO
Catalogue No: abx010781
Price:
US$427.75
(Size: 100 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Research Articles on Fibrinogen Beta (FGB)
| Target | Fibrinogen Beta (FGB) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human FGB (aa30-300) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P02675 (UniProt, ExPASy) |
| UniProt Secondary AC | A0JLR9, B2R7G3, Q32Q65, Q3KPF2 |
| UniProt Entry Name | FIBB_HUMAN |
| Gene Symbol | FGB |
| GeneID | 2244 |
| OMIM | 134830 |
| HGNC | 3662 |
| KEGG | hsa:2244 |
| Ensembl | ENSG00000171564 |
| String | 9606.ENSP00000306099 |
| Molecular Weight | 52 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |