Fibroblast Growth Factor 2 (FGF2) Antibody

FGF2 is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of anguogenesis. Due to its basic pH, the factor is also basic FGF (bFGF). Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FGF1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FGF1).

Target	Fibroblast Growth Factor 2 (FGF2)
Clonality	Monoclonal
Clone	G152
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of FGF2 expressed in E. coli
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P09038 (UniProt, ExPASy)
UniProt Entry Name	FGF2_HUMAN
Gene Symbol	FGF2
GeneID	2247
OMIM	134920
NCBI Accession	NP_001997.5 NM_002006.4
HGNC	3676
KEGG	hsa:2247
Ensembl	ENSG00000138685
String	9606.ENSP00000264498
Molecular Weight	31 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fibroblast Growth Factor 2 (FGF2)

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