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Fibroblast Growth Factor 2 (FGF2) Antibody
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Catalogue No: abx000620
Price:
US$348.00
(Size: 60 µl)
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Fibroblast Growth Factor 2 (FGF2) Antibody is a Rabbit Polyclonal antibody against Fibroblast Growth Factor 2 (FGF2). The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Research Articles on Fibroblast Growth Factor 2 (FGF2)
| Target | Fibroblast Growth Factor 2 (FGF2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human FGF2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09038 (UniProt, ExPASy) P15655 (UniProt, ExPASy) P13109 (UniProt, ExPASy) |
| UniProt Entry Name | FGF2_HUMAN, FGF2_MOUSE, FGF2_RAT |
| Gene Symbol | FGF2 |
| GeneID | 2247 14173 54250 |
| OMIM | 134920 |
| NCBI Accession | NP_001997.5 NM_002006.4 |
| HGNC | 3676 |
| Ensembl | ENSG00000138685, ENSMUSG00000037225, ENSRNOG00000017392 |
| String | 9606.ENSP00000264498 10090.ENSMUSP00000037694 10116.ENSRNOP00000023388 |
| Molecular Weight | Calculated MW: 17 kDa/21 kDa/22 kDa/30 kDa Observed MW: 20 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |