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Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody
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Catalogue No: abx033555
Price:
US$326.25
(Size: 80 µl)
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FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.
Research Articles on Fibroblast Growth Factor Receptor 1 (FGFR1)
| Target | Fibroblast Growth Factor Receptor 1 (FGFR1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 631-660 amino acids from human FGFR1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P11362 (UniProt, ExPASy) |
| UniProt Entry Name | FGFR1_HUMAN |
| KEGG | hsa:2260 |
| String | 9606.ENSP00000393312 |
| Molecular Weight | Calculated MW: 91.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Chicken, Zebrafish and Xenopus FGFR1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |