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Fibrinogen Gamma (FGG) Antibody
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Catalogue No: abx011887
Price:
US$420.50
(Size: 100 µl)
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The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Research Articles on Fibrinogen Gamma (FGG)
| Target | Fibrinogen Gamma (FGG) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human FGG expressed in E. coli. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P02679 (UniProt, ExPASy) |
| UniProt Entry Name | FIBG_HUMAN |
| Gene Symbol | FGG |
| GeneID | 2266 |
| OMIM | 134850 |
| HGNC | 3694 |
| KEGG | hsa:2266 |
| Ensembl | ENSG00000171557 |
| String | 9606.ENSP00000336829 |
| Molecular Weight | 52 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |