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Tyrosine-Protein Kinase Fgr (FGR) Antibody
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Catalogue No: abx033632
Price:
US$326.25
(Size: 80 µl)
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FGR is a member of the Src family of protein tyrosine kinases (PTKs). This protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.
Research Articles on Tyrosine-Protein Kinase Fgr (FGR)
| Target | Tyrosine-Protein Kinase Fgr (FGR) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 3-33 amino acids from the N-terminal region of human FGR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09769 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DPL7, Q9UIQ3 |
| UniProt Entry Name | FGR_HUMAN |
| NCBI Accession | NP_001036194.1 NP_001036212.1 NP_005239.1 |
| KEGG | hsa:2268 |
| String | 9606.ENSP00000363117 |
| Molecular Weight | Calculated MW: 59.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |