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Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody
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Catalogue No: abx011774
Price:
US$406.00
(Size: 100 µg)
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Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody is a Rabbit Polyclonal antibody for the detection of FGFR1. Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processed including embryonic development, cell proliferation, differentiation, migration, and tumorigenesis. Mutations in FGFR1 gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome. Alternatively spliced variants which encode different protein isoforms have been described.
Research Articles on Fibroblast Growth Factor Receptor 1 (FGFR1)
| Target | Fibroblast Growth Factor Receptor 1 (FGFR1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | fibroblast growth factor receptor 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P11362 (UniProt, ExPASy) |
| UniProt Entry Name | FGFR1_HUMAN |
| Gene Symbol | FGFR1 |
| GeneID | 2260 |
| OMIM | 136350 |
| HGNC | 3688 |
| KEGG | hsa:2260 |
| Ensembl | ENSG00000077782 |
| String | 9606.ENSP00000393312 |
| Molecular Weight | Observed MW: 45-55 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |