Fibronectin (FN1) Antibody

Fibronectin (FN1) Antibody is a Rabbit Polyclonal antibody for the detection of Fibronectin.

Fibronectin 1 (FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellular matrix (cellular FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes.Cellular FN (dimeric or cross-linked multimeric forms),made by fibroblasts,epithelial and other cell types,is deposited as fibrils in the extracellular matrix.FN1 binds to cell surfaces through integrins and to various compounds including collagen,fibrin and heparin.It is involved in cell adhesion and migration processes including embryogenesis,wound healing,hemostasis,host defense,and metastasis. (PMID:7276612;12244123;12847088)

Target	Fibronectin (FN1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	fibronectin 1
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P02751 (UniProt, ExPASy)
Gene Symbol	FN1
GeneID	2335
OMIM	135600
HGNC	3778
Ensembl	ENSG00000115414
Molecular Weight	Observed MW: 220-270 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Fibronectin (FN1)

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