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FK506 Binding Protein 5 (FKBP5) Antibody
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Catalogue No: abx002810
Price:
US$203.00
(Size: 20 µl)
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FKBP5 Antibody is a Rabbit Polyclonal antibody against FKBP5. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Research Articles on FK506 Binding Protein 5 (FKBP5)
| Target | FK506 Binding Protein 5 (FKBP5) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 308-457 of human FKBP51/FKBP5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13451 (UniProt, ExPASy) |
| UniProt Secondary AC | F5H7R1, Q59EB8, Q5TGM6 |
| UniProt Entry Name | FKBP5_HUMAN |
| GeneID | 2289 |
| NCBI Accession | NP_001139247.1 |
| KEGG | hsa:2289 |
| String | 9606.ENSP00000444810 |
| Molecular Weight | Calculated MW: 51 kDa Observed MW: 51 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |