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FK506 Binding Protein 3 (FKBP3) Antibody
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Catalogue No: abx005250
Price:
US$217.50
(Size: 20 µl)
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FKBP3 Antibody is a Rabbit Polyclonal antibody against FKBP3. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Research Articles on FK506 Binding Protein 3 (FKBP3)
| Target | FK506 Binding Protein 3 (FKBP3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human FKBP3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q00688 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R4Q9, Q14317 |
| UniProt Entry Name | FKBP3_HUMAN |
| Gene Symbol | FKBP3 |
| GeneID | 2287 |
| NCBI Accession | NP_002004.1 |
| KEGG | hsa:2287 |
| String | 9606.ENSP00000216330 |
| Molecular Weight | Calculated MW: 25 kDa Observed MW: 30 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |