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Folliculin (FLCN) Antibody
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Catalogue No: abx034049
Price:
US$326.25
(Size: 80 µl)
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FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). FLCN may be a tumor suppressor. May be involved in colorectal tumorigenesis. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways.
Research Articles on Folliculin (FLCN)
| Target | Folliculin (FLCN) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 325-354 amino acids from the Central region of human FLCN. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8NFG4 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NJJ8, Q6ZRX1, Q96BD2, Q96BE4 |
| UniProt Entry Name | FLCN_HUMAN |
| Gene Symbol | FLCN |
| KEGG | hsa:201163 |
| String | 9606.ENSP00000285071 |
| Molecular Weight | Calculated MW: 64.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |