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Flavin Containing Monooxygenase 5 (FMO5) Antibody
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Catalogue No: abx031488
Price:
US$326.25
(Size: 80 µl)
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Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.
Research Articles on Flavin Containing Monooxygenase 5 (FMO5)
| Target | Flavin Containing Monooxygenase 5 (FMO5) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 474-502 amino acids from the C-terminal region of human FMO5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49326 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RBG1, C9JJD1, Q8IV22 |
| UniProt Entry Name | FMO5_HUMAN |
| KEGG | hsa:2330 |
| String | 9606.ENSP00000254090 |
| Molecular Weight | Calculated MW: 60.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |