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Fibromodulin (FMOD) Antibody
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Catalogue No: abx004875
Price:
US$217.50
(Size: 20 µl)
Reviews: 
(1 Publications and Reviews)
(1 Publications and Reviews)
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FMOD Antibody is a Rabbit Polyclonal antibody against FMOD. Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.
Research Articles on Fibromodulin (FMOD)
| Target | Fibromodulin (FMOD) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 19-376 of human FMOD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q06828 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15331, Q8IV47 |
| UniProt Entry Name | FMOD_HUMAN |
| Gene Symbol | FMOD |
| GeneID | 2331 |
| OMIM | 600245 |
| NCBI Accession | NP_002014.2 |
| HGNC | 3774 |
| KEGG | hsa:2331 |
| Ensembl | ENSG00000122176 |
| String | 9606.ENSP00000347041 |
| Molecular Weight | Calculated MW: 43 kDa Observed MW: 45 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1.99 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |