Fragile X Mental Retardation 1 (FMR1) Antibody

FMR1 Antibody is a Rabbit Polyclonal antibody against FMR1. The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Target	Fragile X Mental Retardation 1 (FMR1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human FMRP.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q06787 (UniProt, ExPASy)
UniProt Entry Name	FMR1_HUMAN
Gene Symbol	FMR1
GeneID	2332
NCBI Accession	NP_001172011.1
KEGG	hsa:2332
String	9606.ENSP00000359506
Molecular Weight	Calculated MW: 71 kDa Observed MW: 85 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fragile X Mental Retardation 1 (FMR1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue