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Folate Receptor Alpha (FOLR1) Antibody
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Catalogue No: abx025854
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Research Articles on Folate Receptor Alpha (FOLR1)
| Target | Folate Receptor Alpha (FOLR1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/1000, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 33-68 amino acids from the N-terminal region of human FOLR1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P15328 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53EW2, Q6FGT8, Q6LC90, Q9UCT2 |
| UniProt Entry Name | FOLR1_HUMAN |
| Gene Symbol | FOLR1 |
| NCBI Accession | NP_000793.1 NP_057936.1 NP_057937.1 NP_057941.1 |
| KEGG | hsa:2348 |
| String | 9606.ENSP00000377284 |
| Molecular Weight | Calculated MW: 29.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |