+44 (0) 1223 755950
+1 832 327 7413
Fructose-1,6-Bisphosphatase 1 (FBP1) Antibody
REQUEST MORE INFO
Catalogue No: abx215311
Price:
US$406.00
(Size: 100 µg)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Fructose-1,6-Bisphosphatase 1 (FBP1) Antibody is a Rabbit Polyclonal antibody for the detection of FBP1. Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Research Articles on Fructose-1,6-Bisphosphatase 1 (FBP1)
| Target | Fructose-1,6-Bisphosphatase 1 (FBP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | fructose-1,6-bisphosphatase 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P09467 (UniProt, ExPASy) |
| UniProt Secondary AC | O75571, Q53F94, Q96E46 |
| UniProt Entry Name | F16P1_HUMAN |
| Gene Symbol | FBP1 |
| GeneID | 2203 |
| OMIM | 229700 |
| HGNC | 3606 |
| KEGG | hsa:2203 |
| Ensembl | ENSG00000165140 |
| String | 9606.ENSP00000408025 |
| Molecular Weight | Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |