Frizzled Homolog 7 (FZD7) Antibody

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Catalogue No: abx003117
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
FZD7 Antibody is a Rabbit Polyclonal antibody against FZD7. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Target Frizzled Homolog 7 (FZD7)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human FZD7.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O75084 (UniProt, ExPASy)
UniProt Secondary AC O94816, Q53S59, Q96B74
UniProt Entry Name FZD7_HUMAN
Gene Symbol FZD7
GeneID 8324
NCBI Accession NP_003498.1
KEGG hsa:8324
String 9606.ENSP00000286201
Molecular Weight Calculated MW: 64 kDa
Observed MW: 70-72 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Frizzled Homolog 7 (FZD7)


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