GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) Antibody

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Target	GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human G3BP1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13283 (UniProt, ExPASy)
UniProt Secondary AC	Q5HYE9
UniProt Entry Name	G3BP1_HUMAN
KEGG	hsa:10146
String	9606.ENSP00000377681
Molecular Weight	Calculated MW: 52.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Cow G3BP1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1)

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