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Glucose-6-Phosphate Dehydrogenase (G6PD) Antibody
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Catalogue No: abx001294
Price:
US$203.00
(Size: 20 µl)
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G6PD Antibody is a Rabbit Polyclonal antibody against G6PD. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Glucose-6-Phosphate Dehydrogenase (G6PD)
| Target | Glucose-6-Phosphate Dehydrogenase (G6PD) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 195-515 of human G6PD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P11413 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DWX9, Q16000, Q16765, Q8IU70, Q8IU88, Q8IUA6, Q96PQ2 |
| UniProt Entry Name | G6PD_HUMAN |
| Gene Symbol | G6PD |
| GeneID | 2539 |
| NCBI Accession | NP_001035810.1 |
| KEGG | hsa:2539 |
| String | 9606.ENSP00000377192 |
| Molecular Weight | Calculated MW: 59 kDa Observed MW: 59 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |