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GRB2-Associated-Binding Protein 1 (GAB1) Antibody
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Catalogue No: abx010862
Price:
US$420.50
(Size: 100 µl)
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Grb2-associated binding protein 1 is a member of the IRS-1-like multisubstrate docking protein family. Contains an N-terminal pleckstrin homology (PH) domain and several proline-rich SH3 domain-binding sequences. Mediates branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis.
Research Articles on GRB2-Associated-Binding Protein 1 (GAB1)
| Target | GRB2-Associated-Binding Protein 1 (GAB1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human GAB1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13480 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K152, Q4W5G2, Q6P1W2 |
| UniProt Entry Name | GAB1_HUMAN |
| Gene Symbol | GAB1 |
| GeneID | 2549 |
| OMIM | 604439 |
| HGNC | 4066 |
| KEGG | hsa:2549 |
| Ensembl | ENSG00000109458 |
| String | 9606.ENSP00000262995 |
| Molecular Weight | Calculated MW: 76.6 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |