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Gamma-Aminobutyric Acid Receptor Subunit Alpha-4 (gABRA4) Antibody
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Catalogue No: abx002817
Price:
US$348.00
(Size: 60 µl)
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gABRA4 Antibody is a Rabbit Polyclonal antibody against gABRA4. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.
Research Articles on Gamma-Aminobutyric Acid Receptor Subunit Alpha-4 (gABRA4)
| Target | Gamma-Aminobutyric Acid Receptor Subunit Alpha-4 (gABRA4) |
| Clonality | Polyclonal |
| Reactivity | Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human GABRA4 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48169 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8IYR7 |
| UniProt Entry Name | GBRA4_HUMAN |
| Gene Symbol | GABRA4 |
| GeneID | 2557 |
| NCBI Accession | NP_000800.2 |
| KEGG | hsa:2557 |
| String | 9606.ENSP00000264318 |
| Molecular Weight | Calculated MW: 61 kDa Observed MW: 72 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |