DNA Damage Inducible Transcript 3 (DDIT3) Antibody

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Catalogue No: abx010559
Price: US$348.00
(Size: 50 µl)

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Western blot analysis of Jurkat cell lysate using GADD153 Antibody.
DNA Damage Inducible Transcript 3 (DDIT3) Antibody

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Datasheet SDS
GADD153 Antibody detects endogenous levels of GADD153. CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.

Target DNA Damage Inducible Transcript 3 (DDIT3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthesised peptide derived from human GADD153
Form Liquid
Purification Purified by immunogen affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35638 (UniProt, ExPASy)
UniProt Secondary AC F8VS99
UniProt Entry Name DDIT3_HUMAN
Gene Symbol DDIT3
GeneID 1649
OMIM 126337
HGNC 2726
KEGG hsa:1649
Ensembl ENSG00000175197
String 9606.ENSP00000448665
Molecular Weight 26 kDa
Buffer PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Specificity GADD153 Antibody detects endogenous levels of GADD153
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on DNA Damage Inducible Transcript 3 (DDIT3)
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