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N-Acetylgalactosamine 6-Sulfatase (GALNS) Antibody
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Catalogue No: abx026361
Price:
US$290.00
(Size: 80 µl)
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This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq].
Research Articles on N-Acetylgalactosamine 6-Sulfatase (GALNS)
| Target | N-Acetylgalactosamine 6-Sulfatase (GALNS) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 236-263 amino acids from the Central region of human GALNS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P34059 (UniProt, ExPASy) |
| UniProt Secondary AC | Q86VK3 |
| UniProt Entry Name | GALNS_HUMAN |
| Gene Symbol | GALNS |
| KEGG | hsa:2588 |
| String | 9606.ENSP00000268695 |
| Molecular Weight | Calculated MW: 58 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Pig GALNS. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |