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Polypeptide N-Acetylgalactosaminyltransferase 6 (GALNT6) Antibody
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Catalogue No: abx029087
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.
Research Articles on Polypeptide N-Acetylgalactosaminyltransferase 6 (GALNT6)
| Target | Polypeptide N-Acetylgalactosaminyltransferase 6 (GALNT6) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 552-579 amino acids from the C-terminal region of human GALNT6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8NCL4 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8IYH4, Q9H6G2, Q9UIV5 |
| UniProt Entry Name | GALT6_HUMAN |
| Gene Symbol | GALNT6 |
| GeneID | 11226 |
| OMIM | 605148 |
| KEGG | hsa:11226 |
| String | 9606.ENSP00000444171 |
| Molecular Weight | Calculated MW: 71.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow GALNT6. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |