Glycine Amidinotransferase, Mitochondrial (GATM) Antibody

GATM Antibody is a Rabbit Polyclonal antibody against GATM. This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

Target	Glycine Amidinotransferase, Mitochondrial (GATM)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 38-423 of human GATM.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P50440 (UniProt, ExPASy)
UniProt Secondary AC	B4DH99, B4DPI3, Q53EQ4
UniProt Entry Name	GATM_HUMAN
Gene Symbol	GATM
GeneID	2628
NCBI Accession	NP_001473.1
KEGG	hsa:2628
String	9606.ENSP00000379895
Molecular Weight	Calculated MW: 48 kDa Observed MW: 48 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glycine Amidinotransferase, Mitochondrial (GATM)

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