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Glycine Amidinotransferase, Mitochondrial (GATM) Antibody
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Catalogue No: abx005060
Price:
US$203.00
(Size: 20 µl)
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GATM Antibody is a Rabbit Polyclonal antibody against GATM. This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
Research Articles on Glycine Amidinotransferase, Mitochondrial (GATM)
| Target | Glycine Amidinotransferase, Mitochondrial (GATM) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 38-423 of human GATM. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P50440 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DH99, B4DPI3, Q53EQ4 |
| UniProt Entry Name | GATM_HUMAN |
| Gene Symbol | GATM |
| GeneID | 2628 |
| NCBI Accession | NP_001473.1 |
| KEGG | hsa:2628 |
| String | 9606.ENSP00000379895 |
| Molecular Weight | Calculated MW: 48 kDa Observed MW: 48 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |