Grancalcin (GCA) Antibody

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Catalogue No: abx005357
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
GCA Antibody is a Rabbit Polyclonal antibody against GCA. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.

Target Grancalcin (GCA)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GCA.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P28676 (UniProt, ExPASy)
UniProt Secondary AC B2R5X3, Q53TB5, Q59EP3
UniProt Entry Name GRAN_HUMAN
Gene Symbol GCA
GeneID 25801
NCBI Accession NP_036330.1
KEGG hsa:25801
String 9606.ENSP00000394842
Molecular Weight Calculated MW: 24 kDa
Observed MW: 24 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Grancalcin (GCA)


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