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GTP Cyclohydrolase 1 Feedback Regulatory Protein (GCHFR) Antibody
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Catalogue No: abx030682
Price:
US$290.00
(Size: 80 µl)
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GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
Research Articles on GTP Cyclohydrolase 1 Feedback Regulatory Protein (GCHFR)
| Target | GTP Cyclohydrolase 1 Feedback Regulatory Protein (GCHFR) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 38-66 amino acids from the C-terminal region of human GCHFR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P30047 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R4L6, B7ZLM8, Q2M1Q2, Q99749 |
| UniProt Entry Name | GFRP_HUMAN |
| Gene Symbol | GCHFR |
| KEGG | hsa:2644 |
| String | 9606.ENSP00000260447 |
| Molecular Weight | Calculated MW: 9.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow GCHFR. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |