Hexokinase-4 (GCK) Antibody

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Catalogue No: abx015872
Price: US$427.75
(Size: 100 µl)
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Western blot analysis using GCK antibody against human GCK (AA: 1-198) recombinant protein. (Expected MW is 48.2 kDa).
Hexokinase-4 (GCK) Antibody Hexokinase-4 (GCK) Antibody Hexokinase-4 (GCK) Antibody

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Datasheet SDS
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways.Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver.The protein localizes to the outer membrane of mitochondria.In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant.Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Target Hexokinase-4 (GCK)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA
Host Mouse
Recommended dilutions ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human GCK expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35557 (UniProt, ExPASy)
UniProt Secondary AC A4D2J2, A4D2J3, Q05810
UniProt Entry Name HXK4_HUMAN
Gene Symbol GCK
GeneID 2645
OMIM 125851
HGNC 4195
KEGG hsa:2645
Ensembl ENSG00000106633
String 9606.ENSP00000223366
Molecular Weight 52 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Hexokinase-4 (GCK)


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