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Glutamate Cysteine Ligase, Modifier Subunit (GCLM) Antibody
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Catalogue No: abx034226
Price:
US$326.25
(Size: 80 µl)
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GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
Research Articles on Glutamate Cysteine Ligase, Modifier Subunit (GCLM)
| Target | Glutamate Cysteine Ligase, Modifier Subunit (GCLM) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/8000, IHC-P: 1/25, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 246-274 amino acids from the C-terminal region of human GCLM. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48507 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K334, D3DT45, M5A959, Q6FHC1, Q9NPX9, Q9NU74 |
| UniProt Entry Name | GSH0_HUMAN |
| KEGG | hsa:2730 |
| String | 9606.ENSP00000359258 |
| Molecular Weight | Calculated MW: 30.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |