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Glutamate Cysteine Ligase, Modifier Subunit (GCLM) Antibody
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Catalogue No: abx004063
Price:
US$203.00
(Size: 20 µl)
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GCLM Antibody is a Rabbit Polyclonal antibody against GCLM. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
Research Articles on Glutamate Cysteine Ligase, Modifier Subunit (GCLM)
| Target | Glutamate Cysteine Ligase, Modifier Subunit (GCLM) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human GCLM. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48507 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K334, D3DT45, M5A959, Q6FHC1, Q9NPX9, Q9NU74 |
| UniProt Entry Name | GSH0_HUMAN |
| Gene Symbol | GCLM |
| GeneID | 2730 |
| NCBI Accession | NP_002052.1 |
| KEGG | hsa:2730 |
| String | 9606.ENSP00000359258 |
| Molecular Weight | Calculated MW: 31 kDa Observed MW: 31 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 0.375 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |