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Gem Nuclear Organelle Associated Protein 2 (GEMIN2) Antibody
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Catalogue No: abx002220
Price:
US$217.50
(Size: 20 µl)
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GEMIN2 Antibody is a Rabbit Polyclonal antibody against GEMIN2. This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Research Articles on Gem Nuclear Organelle Associated Protein 2 (GEMIN2)
| Target | Gem Nuclear Organelle Associated Protein 2 (GEMIN2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 180-280 of human Gemin 2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O14893 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9W8, Q2M3B3, Q9H4F5, Q9NS77, Q9NS78, Q9NS79 |
| UniProt Entry Name | GEMI2_HUMAN |
| Gene Symbol | GEMIN2 |
| GeneID | 8487 |
| NCBI Accession | NP_003607.1 |
| KEGG | hsa:8487 |
| String | 9606.ENSP00000308533 |
| Molecular Weight | Calculated MW: 32 kDa Observed MW: 35 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |