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GDNF Family Receptor Alpha 1 (GFRA1) Antibody
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Catalogue No: abx004114
Price:
US$348.00
(Size: 60 µl)
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GFRA1 Antibody is a Rabbit Polyclonal antibody against GFRA1. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
Research Articles on GDNF Family Receptor Alpha 1 (GFRA1)
| Target | GDNF Family Receptor Alpha 1 (GFRA1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human GFRA1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P56159 (UniProt, ExPASy) |
| UniProt Secondary AC | A8KA21, O15507, O43912 |
| UniProt Entry Name | GFRA1_HUMAN |
| Gene Symbol | GFRA1 |
| GeneID | 2674 |
| NCBI Accession | NP_005255.1 |
| KEGG | hsa:2674 |
| String | 9606.ENSP00000347591 |
| Molecular Weight | Calculated MW: 50 kDa/51 kDa Observed MW: 51 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |