GDNF Family Receptor Alpha 1 (GFRA1) Antibody

GFRA1 Antibody is a Rabbit Polyclonal antibody against GFRA1. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.

Target	GDNF Family Receptor Alpha 1 (GFRA1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 345-420 of human GFRA1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P56159 (UniProt, ExPASy)
UniProt Secondary AC	A8KA21, O15507, O43912
UniProt Entry Name	GFRA1_HUMAN
Gene Symbol	GFRA1
GeneID	2674
NCBI Accession	NP_005255.1
KEGG	hsa:2674
String	9606.ENSP00000347591
Molecular Weight	Calculated MW: 51 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on GDNF Family Receptor Alpha 1 (GFRA1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue