Growth Hormone Secretagogue Receptor (GHSR) Antibody

This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.

Target	Growth Hormone Secretagogue Receptor (GHSR)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 326-357 amino acids from the C-terminal region of human GHSR.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92847 (UniProt, ExPASy)
UniProt Secondary AC	Q14D12, Q6ISR8, Q92848, Q96RJ7
UniProt Entry Name	GHSR_HUMAN
KEGG	hsa:2693
String	9606.ENSP00000241256
Molecular Weight	Calculated MW: 41.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Pig and Rabbit GHSR.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Growth Hormone Secretagogue Receptor (GHSR)

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