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Growth Hormone Secretagogue Receptor (GHSR) Antibody
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Catalogue No: abx026483
Price:
US$290.00
(Size: 80 µl)
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This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
Research Articles on Growth Hormone Secretagogue Receptor (GHSR)
| Target | Growth Hormone Secretagogue Receptor (GHSR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 326-357 amino acids from the C-terminal region of human GHSR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q92847 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14D12, Q6ISR8, Q92848, Q96RJ7 |
| UniProt Entry Name | GHSR_HUMAN |
| KEGG | hsa:2693 |
| String | 9606.ENSP00000241256 |
| Molecular Weight | Calculated MW: 41.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig and Rabbit GHSR. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |