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Gastric Inhibitory Polypeptide Receptor (GIPR) Antibody
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Catalogue No: abx033435
Price:
US$326.25
(Size: 80 µl)
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GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
Research Articles on Gastric Inhibitory Polypeptide Receptor (GIPR)
| Target | Gastric Inhibitory Polypeptide Receptor (GIPR) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48546 (UniProt, ExPASy) |
| UniProt Secondary AC | B7WP14, B7ZKQ0, Q14401, Q16400, Q52M04, Q9UPI1 |
| UniProt Entry Name | GIPR_HUMAN |
| NCBI Accession | NP_000155.1 |
| KEGG | hsa:2696 |
| String | 9606.ENSP00000467494 |
| Molecular Weight | Calculated MW: 53.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |