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GIT1 (pY554) Antibody
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Catalogue No: abx032028
Price:
US$326.25
(Size: 80 µl)
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GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization, increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. It sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes.
Research Articles on GIT1 (pY554)
| Target | GIT1 (pY554) |
| Clonality | Polyclonal |
| Target Modification | Tyr554 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y554 of human GIT1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y2X7 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DGU9, B4DSV3, Q86SS0, Q9BRJ4 |
| UniProt Entry Name | GIT1_HUMAN |
| String | 9606.ENSP00000378338 |
| Molecular Weight | Calculated MW: 84.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat GIT1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |