Gap Junction Protein Beta 2 (GJB2) Antibody

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Catalogue No: abx028496
Price: US$326.25
(Size: 80 µl)

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Gap Junction Protein Beta 2 (GJB2) Antibody
Gap Junction Protein Beta 2 (GJB2) Antibody Gap Junction Protein Beta 2 (GJB2) Antibody

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Datasheet SDS
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Immunohistochemical staining of human cochlear cells demonstrated high levels of GJB2 expression. Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.

Target Gap Junction Protein Beta 2 (GJB2)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 204-226 amino acids from the C-terminal region of human GJB2.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P29033 (UniProt, ExPASy)
UniProt Entry Name CXB2_HUMAN
NCBI Accession NP_003995.2
KEGG hsa:2706
String 9606.ENSP00000372295
Molecular Weight Calculated MW: 26.2 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Cow and Sheep GJB2.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Gap Junction Protein Beta 2 (GJB2)
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