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Galactosidase Alpha (GLA) Antibody
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Catalogue No: abx001425
Price:
US$203.00
(Size: 20 µl)
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GLA Antibody is a Rabbit Polyclonal antibody against GLA. This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Research Articles on Galactosidase Alpha (GLA)
| Target | Galactosidase Alpha (GLA) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 150-429 of human Galactosidase alpha (GLA). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P06280 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6LER7 |
| UniProt Entry Name | AGAL_HUMAN |
| Gene Symbol | GLA |
| GeneID | 2717 |
| NCBI Accession | NP_000160.1 |
| KEGG | hsa:2717 |
| String | 9606.ENSP00000218516 |
| Molecular Weight | Calculated MW: 49 kDa Observed MW: 49 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |