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Glycine Dehydrogenase (GLDC) Antibody
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Catalogue No: abx034398
Price:
US$326.25
(Size: 80 µl)
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Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Research Articles on Glycine Dehydrogenase (GLDC)
| Target | Glycine Dehydrogenase (GLDC) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GLDC. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P23378 (UniProt, ExPASy) |
| UniProt Secondary AC | Q2M2F8 |
| UniProt Entry Name | GCSP_HUMAN |
| Gene Symbol | GLDC |
| KEGG | hsa:2731 |
| String | 9606.ENSP00000370737 |
| Molecular Weight | Calculated MW: 113 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |