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Glycine Receptor Beta (GLRB) Antibody
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Catalogue No: abx028425
Price:
US$326.25
(Size: 80 µl)
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This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
Research Articles on Glycine Receptor Beta (GLRB)
| Target | Glycine Receptor Beta (GLRB) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48167 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K3K2, D3DP23, F5GWE1 |
| UniProt Entry Name | GLRB_HUMAN |
| KEGG | hsa:2743 |
| String | 9606.ENSP00000264428 |
| Molecular Weight | Calculated MW: 56.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow GLRB. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |