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Glutaredoxin 1 (GLRX) Antibody
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Catalogue No: abx004064
Price:
US$348.00
(Size: 60 µl)
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GLRX Antibody is a Rabbit Polyclonal antibody against GLRX. This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
Research Articles on Glutaredoxin 1 (GLRX)
| Target | Glutaredoxin 1 (GLRX) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human GLRX |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35754 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R4L2, Q3KQS1, Q6ICT1 |
| UniProt Entry Name | GLRX1_HUMAN |
| Gene Symbol | GLRX |
| GeneID | 2745 |
| NCBI Accession | NP_002055.1 |
| KEGG | hsa:2745 |
| String | 9606.ENSP00000369314 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |