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Glutaminase (GLS) Antibody
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Catalogue No: abx034114
Price:
US$326.25
(Size: 50 µl)
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Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.
Research Articles on Glutaminase (GLS)
| Target | Glutaminase (GLS) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/500, IF/ICC: 1/25, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 516-545 amino acids from the C-terminal region of human GLS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O94925 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UL05, Q9UL06, Q9UL07, Q9UN40 |
| UniProt Entry Name | GLSK_HUMAN |
| Gene Symbol | GLS |
| NCBI Accession | NP_001243239.1 NP_055720.3 |
| KEGG | hsa:2744 |
| String | 9606.ENSP00000317379 |
| Molecular Weight | Calculated MW: 73.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat GLS. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |