+44 (0) 1223 755950
+1 832 327 7413
Glutamate Decarboxylase 2 (GAD2) Antibody
REQUEST MORE INFO
Catalogue No: abx415097
Price:
US$565.50
(Size: 100 µg)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Glutamate Decarboxylase 2 (GAD2) Antibody is a Mouse Monoclonal antibody against Glutamate Decarboxylase 2 (GAD2). This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Research Articles on Glutamate Decarboxylase 2 (GAD2)
| Target | Glutamate Decarboxylase 2 (GAD2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | WB, IHC, IP, RIA |
| Host | Mouse |
| Recommended dilutions | Validated in IHC-F and IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Epitope Region | N-terminal |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q05329 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UD87 |
| UniProt Entry Name | DCE2_HUMAN |
| Gene Symbol | GAD2 |
| GeneID | 2572 |
| OMIM | 138275 |
| NCBI Accession | NM_000818.2 NM_001134366.1 |
| HGNC | 4093 |
| KEGG | hsa:2572 |
| Ensembl | ENSG00000136750 |
| String | 9606.ENSP00000365437 |
| Buffer | PBS. Contains sodium azide. |
| Concentration | 1.0 mg/ml |
| Availability | Shipped within 3-7 working days. |
| Note | This product is for research use only. |