Glutathione Synthetase (GSS) Antibody

Glutathione Synthetase (GSS) Antibody is a Rabbit Polyclonal antibody for the detection of GSS.

Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Target	Glutathione Synthetase (GSS)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Glutathione synthetase
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P48637 (UniProt, ExPASy)
UniProt Secondary AC	B2R697, B6F210, E1P5P9, Q4TTD9
UniProt Entry Name	GSHB_HUMAN
Gene Symbol	GSS
GeneID	2937
OMIM	231900
HGNC	4624
KEGG	hsa:2937
Ensembl	ENSG00000100983
String	9606.ENSP00000216951
Molecular Weight	Observed MW: 54 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Glutathione Synthetase (GSS)

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