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Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody
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Catalogue No: abx240154
Price:
US$406.00
(Size: 100 µg)
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Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody is a Mouse Monoclonal antibody for the detection of GSK3B. The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Glycogen Synthase Kinase-3 Beta (GSK3B)
| Target | Glycogen Synthase Kinase-3 Beta (GSK3B) |
| Clonality | Monoclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | glycogen synthase kinase 3 beta |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P49841 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DN89, Q9BWH3, Q9UL47 |
| UniProt Entry Name | GSK3B_HUMAN |
| Gene Symbol | GSK3B |
| GeneID | 2932 |
| OMIM | 605004 |
| HGNC | 4617 |
| KEGG | hsa:2932 |
| Ensembl | ENSG00000082701 |
| String | 9606.ENSP00000324806 |
| Molecular Weight | Observed MW: 47 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |